Literature Review Matrix Template

Research question not specified. Research problem relates to a lack of knowledge pertaining to the relationship between statins and blood thrombogenicity. Quantitative methods, quasi-experimental pre-test, post-test.Two different stain treatment groups, lipid profiles measured via AspirinWorks assay. Logistical regression, analysis of variance. Patients on statins significantly lower cholesterol, LDL. Statins combined with aspirin offer migraine relief, anti-inflammatory, and antithrombotic effects. Scientifically rigorous design controlled for bias. Evidence for selective reporting, not all details of the study presented. Aspirin combined with statins a potentially efficacious therapy.

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References

Chaudhary, R., Bliden, K. P., Garg, J., Mohammed, N., Tantry, U., Mathew, D., ... Gurbel, P. (2016). Statin therapy and inflammation in patients with diabetes treated with high dose aspirin. Journal of Diabetes and Its Complications, 30(7), 1365-1370.

Katsiki, N., G Athyros, V., Karagiannis, A., P Mikhailidis, D. (2016). Statins and type 2 diabetes mellitus: An update after 1 year. Current Pharmaceutical Design, 22(18), 2723-2725.

Olesen, K. K., Madsen, M., Egholm, G., Thim, T., Jensen, L. O., Raungaard, B., ... Maeng, M. (2017). Patients with diabetes without significant angiographic coronary artery disease have the same risk of myocardial infarction as patients without diabetes in a real-world population receiving appropriate prophylactic treatment. Diabetes Care, 40(8), 1103-1110.

Schmidt, M., Maeng, M., Madsen, M., Sørensen, H. T., Jensen, L. O., Jakobsen, C. J. (2018). The Western Denmark heart registry: Its influence on cardiovascular patient care. Journal of the American College of Cardiology, 71(11), 1259-1272.

Signorelli, S. S., Katsiki, N. (2018). Oxidative stress and inflammation: Their role in the pathogenesis of peripheral artery disease with or without type 2 diabetes mellitus. Current Vascular Pharmacology, 16(6), 547-554.

Zhang, X., Ran, X., Xu, Z., Cheng, Z., Shen, F., Yu, Y., ...Liu, J. (2018). Epidemiological characteristics of lower extremity arterial disease in Chinese diabetes patients at high risk: A prospective, multicenter, cross-sectional study. Journal of Diabetes and Its Complications, 32(2), 150-156.